a blog about Kilt and her kids plus Trouble our JRT mascot.

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Sequim, Washington, United States

Friday, March 19, 2010

NEW PRINCIPLES OF IMMUNOLOGY Jean Dodds DVM

Most recent data from Jean Dodds DVM

"Dogs and cats immune systems mature fully at 6 months. If a modified live virus (MLV) vaccine is given after 6 months of age, it produces an immunity which is good for the life of the pet (i.e: canine distemper, parvo, feline distemper). If another MLV vaccine is given a year later, the antibodies from the first vaccine neutralize the antigens of the second vaccine and there is little or no effect. The titer is not "boosted" nor are more memory cells induced." Not only are annual boosters for parvo and distemper unnecessary, they subject the pet to potential risks of allergic reactions and immune-mediated hemolytic anemia. "There is no scientific documentation to back up label claims for annual administration of MLV vaccines." Puppies receive antibodies through their mother's milk. This natural protection can last 8-14 weeks.

PUPPIES
Puppies & kittens should NOT be vaccinated at LESS than 8 weeks. Maternal immunity will neutralize the vaccine and little protection (0-38%) will be produced. Vaccination at 6 weeks will, however, delay the timing of the first highly effective vaccine. Vaccinations given 2 weeksapart suppress rather than stimulate the immune system. A series of vaccinations is given starting at 8 weeks and given 3-4 weeks apart up to 16 weeks of age. Another vaccination given sometime after 6 months of age (usually at 1 year 4 months) will provide lifetime immunity.

DISTEMPER & PARVO
"According to Dr. Schultz, AVMA, 8-15-95, when a vaccinations series given at 2, 3 & 4 months and again at 1 year with MLV, puppies and kitten program memory cells that survive for life, providing lifelong immunity." Dr. Carmichael at Cornell and Dr. Schultz has studies showing immunity against challenge at 2-10 years for canine distemper & 4 years for parvovirus. Studies for longer duration are pending. "There are no new strains of parvovirus as one manufacturer would like to suggest. Parvovirus vaccination provides cross immunity for all types." Hepatitis (Adenovirus) is one of the agents known to be a cause of kennel cough. Only vaccines with CAV-2 should be used as CAV-1 vaccines carry the risk of "hepatitis blue-eye" reactions & kidney damage.
Distemper (MLV) (e.g. Intervet Progard Puppy)
9 weeks12 weeks16 - 20 weeks
At 1 year MLV Distemper/ Parvovirus only
None needed.Duration of immunity 7.5 / 15 years by studies. Probably lifetime. Longer studies pending.
Can have numerous side effects if given too young (< 8 weeks).
Parvovirus (MLV)(e.g. Intervet Progard Puppy)
9 weeks12 weeks16 - 20 weeks
At 1 year MLV Distemper/ Parvovirus only
None needed. Duration of immunity 7.5 years by studies. Probably lifetime. Longer studies pending.
*At 6 weeks of age, only 30% of puppies are protected but 100% are exposed to the virus at the vet clinic.


BORDATELLA Parainfluenza
Commonly called "Kennel cough". Recommended only for those dogs boarded, groomed, taken to dog shows, or for any reason housed where exposed to a lot of dogs. The intranasal vaccine provides more complete and more rapid onset of immunity with less chance of reaction. Immunity requires 72 hours and does not protect from every cause of kennel cough. Immunity is of short duration (4 to 6 months).**
Bordetella(Intranasal)(killed)
Only recommended 3 days prior to boarding when required. Protects against 2 of the possible 8 causes of kennel cough.


RABIES
There have been no reported cases of rabid dogs or cats in Harris, Montgomery or Ft. Bend Counties [ Texas ] but there have been rabid skunks and bats so the potential exists. It is a killed vaccine and must be given every year.
Rabies(killed)
24 weeks or older
At 1 year (give 3-4 weeks apart from Dist/Parvo booster) Killed 3 year rabies vaccine
3 yr. vaccine given as required by law in California (follow your state/provincial requirements)
rabid animals may infect dogs.

LYME disease
Lyme disease is a tick born disease which can cause lameness, kidney failure and heart disease in dogs. Ticks can also transmit the disease to humans. The original Ft. Dodge killed bacteria has proven to be the most effective vaccine. Lyme disease prevention should emphasize early removal of ticks. Amitraz collars are more effective than Top Spot, as amitraz paralyzes the tick's mouthparts preventing transmission of disease.
1) Low risk in California.
2) 85% of cases are in 9 New England states and Wisconsin.
3) Possible side effect of polyarthritis from whole cell bacterin.

VACCINATIONS NOT RECOMMENDED
Multiple components in vaccines compete with each other for the immune system and result in lesser immunity for each individual disease as well as increasing the risk of a reaction.
Canine Corona Virus is only a disease of puppies. It is rare, self limiting (dogs get well in 3 days without treatment). Cornell & Texas A&M have only diagnosed one case each in the last 7 years. Corona virus does not cause disease in adult dogs.
Leptospirosis vaccine is a common cause of adverse reactions in dogs. Most of the clinical cases of lepto reported in dogs in the US are caused by serovaars (or types) grippotyphosa and bratsilvia. The vaccines contain different serovaars eanicola and ictohemorrhagica. Cross protection is not provided and protection is short lived . Lepto vaccine is immuno-supressive to puppies less than 16 weeks.

NEW DEVELOPMENTS
Giardia is the most common intestinal parasite of humans in North America , 30% or more of all dogs & cats are infected with giardia. It has now been demonstrated that humans can transmit giardia to dogs & cats and vice versa.

VACCINES BADLY NEEDED
New vaccines in development include: Feline Immunodeficiency Virus and cat scratch fever vaccine for cats and Ehrlichia [one of the other tick diseases, much worse than Lyme] for dogs.

THE VIEW FROM THE TRENCHES
Most vets recommend annual boosters and most kennel operators require them. For years, the pricing structure of vets has misled clients into thinking that the inherent value of an annual office visit was in the "shots". They failed to emphasize the importance of a physical exam for early detection of treatable diseases.

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